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GSK 5182

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  • Inhibitors & Agonists
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GSK5182
T8370877387-37-6
GSK5182 is a highly selective inverse estrogen-related receptor γ agonist (IC50 : 79 nM)
  • $48
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(E/Z)-GSK5182
T77092699724-40-6
(E/Z)-GSK5182 (GSK5182(Z/E)) is a racemic mixture comprising (E)-GSK5182 and (Z)-GSK5182 isomers. It acts as a highly selective and orally active inverse agonist for the estrogen-related receptor γ (ERRγ), demonstrating potency with an IC50 of 79 nM. Additionally, GSK5182 is known to induce the generation of reactive oxygen species (ROS) in hepatocellular carcinoma.
  • $93
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